3 Potential Uses For DMAE
By Tyler Woodward
What Is DMAE?:
DMAE is technically known as Dimethylaminoethanol and is an analogue to diethylaminoethanol which is a precursor to choline. Choline is the precursor to the excitatory neurotransmitter acetylcholine and it’s believed that DMAE functions by increasing the amount of acetylcholine in the brain. Acetylcholine in the brain is the primary neurotransmitter involved in learning and memory.
DMAE is produced in small quantities naturally in the body and is also found in higher concentrations in fatty fish like salmon, sardines and anchovies. DMAE is also used in pharmaceutical drugs including:
Benefits Of DMAE:
DMAE is thought to have a number of proposed benefits including:
- May Help Alzheimer’s - One of the main theories currently proposed to cause Alzheimer's disease is a decline in the production of the neurotransmitter acetylcholine. In animal studies it has been shown that DMAE has been able to increase choline levels and may actually cross the blood-brain barrier better than choline. A number of anecdotal evidence has also been found that DMAE has been shown to improve memory and cognition.
- May Improve Attention And Focus In Children - Drugs like ritalin and adderall are often prescribed to children to improve their ability to focus in school. As these drugs are increasingly recognized as dangerous to children other alternatives are being considered like DMAE. Two studies performed in 1974 and 1975 found that DMAE had similar effects to Ritailin and methylphenidate.
- Reduce Wrinkles And Sagging Skin - A study performed by the American Journal of Dermatology found that DMAE found that a facial gel containing 3% DMAE reduced fine lines around the eyes and forehead. Another study found in humans and mice that DMAE may hydrate skin and improve appearance.
Who Should Not Take DMAE?:
DMAE should not be taken by pregnant women as one study in animals found that DMAE may be linked to causing spina bifida. Additionally, there are a number of drugs that should not be mixed with DMAE as they could cause adverse reactions or render the medication ineffective. These drugs include:
- Acetylcholinesterase Inhibitors - A drug that inhibits the breakdown of choline and is most commonly used in dementia patients
- Anticholinergic Medications - Drugs that inhibit the production of choline like Parkinson’s Disease and COPD.
- Cholinergic Medications - Similar to DMAe these drugs are designed to increase choline production or mimic the effects of choline in the brain.
- Anticoagulants - Drugs that thin the blood, preventing the clotting of blood in the bloodstream.
Lastly, those with bipolar disorder, schizofrenia or epilepsy should exercise caution when using DMAE and should make sure to get medical advice prior to using.
Best Sources Of DMAE:
DMAE used to be sold as a pharmaceutical medication for children, but today it can only be found in supplement form in addition to topical medication. Depending on your goals from supplementing with DMAE you may want to consider using topical DMAE for skin health and supplemental DMAE if you’re looking to boost cognitive performance. Additionally, it’s important to ensure that the company which you purchase your product from is high-quality and uses rigorous heavy metal and purity testing.
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