Christopher Walker | August 3, 2023
Where Does Collagen Come From? How Is It Made in the Body?
Collagen is often talked about as a beauty nutrient or joint-supporting protein, but the truth is much deeper. Collagen is the most abundant protein in the human body, forming the structural framework for skin, bones, tendons, ligaments, cartilage, and even parts of the digestive tract. It provides strength, elasticity, and integrity to tissues that need to stretch, bear weight, or withstand constant movement.
But where exactly does collagen come from, and how does the body actually make it?
To understand the value of collagen-rich foods and supplements, it helps to understand how this essential protein is produced, what nutrients it relies on, and why collagen naturally changes throughout life.
What Is Collagen Made Of?
Collagen is a protein built from long chains of amino acids, mainly glycine, proline, and hydroxyproline. These amino acids join together to form rope-like fibers that create strong, flexible structures.
There are many different collagen “types,” but in the human body, the most common are:
-
Type I - Found in skin, bones, tendons, ligaments
-
Type III - Found in skin, blood vessels, and internal organs
-
Type II - Found in cartilage and joints
Most collagen supplements supply Types I and III because they’re the most widespread and support many foundational tissues.
Where Does Collagen Come From in Food?
Humans traditionally consumed collagen from whole-animal foods, particularly the parts that require long cooking times:
-
bones and bone broth
-
tendons
-
ligaments
-
skin
-
connective tissue–rich cuts of meat
These foods are rich in gelatin (cooked collagen) and glycine which are amino acids that support the body’s collagen-building pathways.
However, modern diets rarely include these cuts. Most people rely heavily on lean muscle meats, which contain very little natural collagen. This shift has made collagen supplementation more relevant for individuals looking to increase intake of glycine and connective-tissue amino acids.
How the Body Makes Collagen
Even though collagen can be consumed through food or supplements, the body is fully capable of producing its own collagen, provided it has the right materials.
Here’s a step-by-step look at how collagen is made internally.
1. It Starts With Amino Acids
The body needs a steady supply of:
-
Glycine
-
Proline
-
Hydroxyproline
Glycine is especially important but is often underconsumed in modern diets. When the body doesn’t receive enough glycine from food, collagen production may not operate at full efficiency.
Collagen-rich foods, gelatin, and hydrolyzed collagen powder are excellent sources of these amino acids.
2. Vitamin C Is Required to Build Collagen Fibers
Vitamin C plays a central role in collagen production. It is required as a cofactor for the enzymes that stabilize and link collagen fibers together.
Without enough vitamin C, the body can’t efficiently form the strong triple-helix structure that defines collagen.
This is why many collagen supplements include vitamin C or are often recommended to be taken alongside a vitamin C–rich food or beverage.
3. The Body Uses Enzymes to Assemble the Collagen Helix
Once the amino acids are available, special enzymes in connective-tissue cells (called fibroblasts) begin assembling them into a helix, a twisting, rope-like structure that creates strength and flexibility.
Minerals such as copper and zinc also help support this process by assisting collagen-related enzymes.
4. Collagen Fibers Are Then Cross-Linked for Strength
After assembly, collagen fibers undergo cross-linking, essentially forming internal “bridges” that give tissues their durability.
This is how tendons can stretch without tearing, how skin stays firm, and how connective tissue maintains its structural integrity.
Why Collagen Production Naturally Declines Over Time
Beginning in the late 20s and early 30s, collagen turnover slowly decreases. This is a natural part of aging and isn’t inherently negative, but it does mean the body may not rebuild or maintain connective tissues at the same rate as before.
Factors that influence collagen production include:
-
natural hormonal changes
-
lower glycine intake
-
stress and elevated cortisol
-
reduced vitamin C intake
-
environmental stressors
-
sun exposure
-
low protein diets
-
sleep deprivation
These factors don’t “damage” collagen in a medical sense, but they can influence how efficiently the body maintains connective tissues.
Because of this, many people choose to support collagen production through dietary choices, lifestyle habits, and consistent intake of collagen-rich foods or supplements.
What Helps the Body Maintain Strong Collagen?
Several nutrients and lifestyle practices help support the body’s natural collagen-building process:
1. Adequate Protein Intake
Collagen synthesis depends on amino acids, especially glycine. Ensuring adequate daily protein helps maintain a supply of raw materials.
2. Vitamin C–Rich Foods
Citrus, berries, peppers, and leafy greens help support collagen assembly.
3. Copper and Zinc
Found in shellfish, beef, and nuts, these minerals assist collagen enzymes.
4. Balanced Thyroid Function & Metabolic Energy
From a bioenergetic perspective, collagen synthesis depends on a sufficient energy supply. A well-fed system supports more efficient collagen turnover.
5. Sleep & Stress Management
Collagen-producing cells are sensitive to stress hormones. Balanced cortisol and restorative sleep help support normal connective tissue maintenance.
Why Collagen Supplementation Has Become Popular
While the body is fully capable of making collagen, supplementation offers a convenient way to provide the exact amino acids needed for collagen synthesis, especially glycine, which is often underrepresented in modern diets.
Hydrolyzed collagen peptides are easy to digest and absorb, making them a widely used option for people who want to support:
-
skin hydration and texture
-
joint comfort
-
hair and nail strength
-
gut lining integrity
-
and overall connective tissue resilience
Collagen supplements don’t replace the body’s natural production; they support it by supplying the raw building blocks.
A Natural Next Step: Why Many People Choose zuCollagen
If you’re looking for a simple way to support your body’s natural collagen-building process, zuCollagen offers a clean and effective option. It provides hydrolyzed collagen peptides (Types I & III) the same amino acids the body uses to build connective tissues along with vitamin C to support collagen synthesis and digestive enzymes to support absorption.
Because zuCollagen supplies the foundational building blocks your body already relies on, many people find it easy to add to their daily routine. It blends smoothly into coffee, smoothies, and baked goods, making it a convenient way to increase glycine-rich protein intake and nourish tissues from within.
If your goal is to support skin hydration, joint comfort, strong hair and nails, or the resilience of your connective tissues, zuCollagen provides a straightforward, whole-body approach rooted in how collagen is naturally made.