Zachary Stephens | March 18, 2025

GLP-1 & Weight Loss: The Truth Behind the Trend

Weight Loss

GLP-1: The Latest Craze

Glucagon-like Peptide-1 (GLP-1) has become a major buzzword in both the nutrition and pharmaceutical industries, largely due to the rise of GLP-1 agonists. What started as a promising prescription treatment for type 2 diabetes has now exploded into one of the biggest weight loss trends in recent memory. But what exactly is GLP-1, how does it help with weight loss, and is a prescription the only way to support its benefits? Let’s break it down.

What is GLP-1?

GLP-1 is a peptide hormone produced in the gut in response to food intake. While it was only discovered about 30 years ago, research has shown that GLP-1 plays a crucial role in metabolism, digestion, and blood sugar support. The pharmaceutical industry quickly took notice, developing GLP-1-based drugs that, as ScienceDirect puts it, “are now exploited in the management of type 2 diabetes.”1

Given the current weight loss frenzy, one could easily swap "type 2 diabetes" for "weight loss", and with an emphasis on exploited.

While the weight loss world fixates on GLP-1's ability to support healthy blood sugar levels and curb appetite, this peptide does much more than that. It supports healthy gut motility, helping food move efficiently through the digestive tract. Additionally, research has shown that GLP-1 has cardiovascular and neuroprotective properties. Benefits that not only support healthy weight loss but also contribute to overall well-being far beyond the number on the scale.

What Are GLP-1 Agonists

GLP-1 agonists are prescription medications primarily used to treat type 2 diabetes (T2D) and obesity. Their main function is to lower blood sugar and support metabolic health. However, like most pharmaceuticals, they come with potential side effects.

If you’re considering GLP-1 agonists, it’s essential to consult your doctor first. Your healthcare provider can offer personalized guidance based on your medical history, especially if you have T2D.

Can You Increase GLP-1… Naturally?

You might be thinking, “But Zach, I’m not like those Instagram fitness influencers. I don’t want to inject myself with needles!”

Good news: your body already produces GLP-1 naturally! In fact, every time you eat, your body releases GLP-1 to help support healthy blood sugar and metabolism. When blood sugar is supported, your metabolism runs more efficiently, helping to support weight management naturally. 

But what if your GLP-1 production isn’t optimal? If you struggle with mid-day mood swings or metabolic imbalances, there are natural ways to enhance GLP-1 secretion.

  • Macronutrient Balance Matters – Carbohydrates and fats stimulate GLP-1 release more effectively than protein (at least in animal studies).2

  • Slow-Digesting Carbs Help – Low-glycemic, slow-digesting carbs can lead to prolonged GLP-1 secretion, helping curb appetite for longer.

  • Nutrient Pairing is Key – Combining carbs with fats and protein (e.g., potatoes with butter) can regulate blood sugar better than eating carbs alone. Eating all three macronutrients together can further extend GLP-1 benefits.

Sensolin GLP-1: A Natural Way to Support GLP-1

Sensolin GLP-1 contains dihydroberberine, a more bioavailable and potent form of berberine, shown to support GLP-1 secretion while also supporting healthy blood sugar levels.3

Because dihydroberberine is more efficiently absorbed than standard berberine, you can take less while experiencing greater benefits.

Instead of forcing your body’s metabolic processes with synthetic drugs, Sensolin GLP-1 works with your body to naturally support healthy glucose levels, weight management, and overall wellness.

The Bottom Line

GLP-1 is an important hormone for metabolism and weight regulation and you can formulate your diet or take a supplement to harness its benefits. Instead of chasing the latest weight loss craze, consider supporting your body’s natural GLP-1 production with targeted nutrition.

With Sensolin GLP-1, you can give your metabolism the support it needs, naturally.

References

  1. Marathe, C. S., Rayner, C. K., Jones, K. L., & Horowitz, M. (2013). Glucagon-like peptides 1 and 2 in health and disease: a review. Peptides, 44, 75–86. https://doi.org/10.1016/j.peptides.2013.01.014

  2. Wu, T., Rayner, C. K., Jones, K., & Horowitz, M. (2010). Dietary effects on incretin hormone secretion. Vitamins and hormones, 84, 81–110. https://doi.org/10.1016/B978-0-12-381517-0.00003-5

  3. Araj-Khodaei, M., Ayati, M. H., Azizi Zeinalhajlou, A., Novinbahador, T., Yousefi, M., Shiri, M., Mahmoodpoor, A., Shamekh, A., Namazi, N., & Sanaie, S. (2024). Berberine-induced glucagon-like peptide-1 and its mechanism for controlling type 2 diabetes mellitus: a comprehensive pathway review. Archives of physiology and biochemistry, 130(6), 678–685. https://doi.org/10.1080/13813455.2023.2258559